References - Air Pollution's Effect on the Brain
1. Calderon-Garciduenas L, Mora-Tiscareno A, Ontiveros E, et al. Air pollution, cognitive deficits and brain abnormalities: a pilot study with children and dogs. Brain Cogn. 2008 Nov;68(2):117-27.
2. Calderon-Garciduenas L, Solt AC, et al. Long-term air pollution exposure is associated with neuroinflammation, an altered innate immune response, disruption of the blood-brain barrier, ultrafine particulate deposition, and accumulation of amyloid beta-42 and alpha-synuclein in children and young adults. Toxicol Pathol. 2008;36(2):289-310.
3. Calderon-Garciduenas L, Franco-Lira M, Torres-Jardon R. Pediatric Respiratory and Systemic Effects of Chronic Air Pollution Exposure: Nose, Lung, Heart, and Brain Pathology. Toxicol Pathol, Vol. 35, No1, 154-162 (2007)
4. Hartz A, Bauer B, Block M, Diesel exhaust particles induce oxidative stress, proinflammatory signaling, and P-glycoprotein, up-regulation at the blood-brain barrier. The FASEB Journal 2008;22:2723-2733.
5. Cruts B, van Etten L, Tornquvist H, et al. Exposure to diesel exhaust induces changes in EEG in human volunteers. Part Fibre Toxicol. 2008;5:4. March11. dol:1186/1743-8977-5-4.
6. Suglia SF, et al. Association of Black Carbon with Cognition among Children in a Prospective Birth Cohort Study Am J Epidemiology 2008 167:280-286.
7. Wang, Z., Zeng, X, Zeng, Y, Wang, S. Chen, S. Association of traffic-related air pollution with children's neurobehavioral functions in Quanzhou, China. Environ Health Perspect. 2009 Oct; 117 (10):1612-8
8. Volk H, Hertz-Picciotto I, Delwiche L , Lurmann F, McConnell R. Residential Proximity to Freeways and Autism in the CHARGE study. Environ Health Perspect. 2010 Dec 13. PMID: 21156395.
9. Morales, E., Julvez, J., Torrent, M., et al. Association of Early-life Exposure to Household Gas Appliances and Indoor Nitrogen Dioxide With Cognition and Attention Behavior in Preschoolers. American Journal of Epidemiology 2009 169(11):1327-1336;
10. Suzuki, T., Oshio, S., Iwata, M., et al. In utero exposure to a low concentration of diesel exhaust affects spontaneous locomotor activity and monoaminergic system in male mice. Particle and Fibre Toxicology 2010, 7:7doi:10.1186/1743-8977-7-7
11. Freire, C., Ramos, R., Puertas, R., et al. Association of traffic-related air pollution with cognitive development in children. J Epidemiol Community Health 2010;64:223-228
12. Edwards SC, Jedrychowski W, Butscher M, Camann D, Kieltyka A, Mroz E, et al. 2010. Prenatal Exposure to Airborne Polycyclic Aromatic Hydrocarbons and Children's Intelligence at Age 5 in a Prospective Cohort Study in Poland. Environ Health Perspect :-. doi:10.1289/ehp.0901070
13. Calderon-Garciduenas L, Reed W, Maronpot RR, Henriquez-Roldan C, Delgado-Chavez R, Calderon-Garciduenas A, Dragustinovis I, Franco-Lira M, Aragon-Flores M, Solt AC, Altenburg M, Torres-Jardon R, Swenberg JA. Brain inflammation and Alzheimer's-like pathology in individuals exposed to severe air pollution. Toxicol Pathol. 2004 Nov-Dec;32(6):650-8.
14. Power MC, Weisskopf MG, Alexeeff SE, Coull BA, Spiro Iii A, Schwartz J. Traffic-Related Air Pollution and Cognitive Function in a Cohort of Older Men. Harvard School of Public Health. Environ Health Perspect. 2010 Dec 20.
15. G. Oberdorster, Z. Sharp, V. Atudorei, A. Elder, R. Gelein, W. Kreyling and C. Cox. Translocation of Inhaled Ultrafine Particles to the Brain. Inhalation Toxicology 2004, Vol. 16, No. 6-7, Pages 437-445
16. Perera, FP, L Zhigang, R Whyatt, L Hoepner, S Wang, D Camann and V Rauh. 2009. 2009. Prenatal airborne polycyclic aromatic hydrocarbon exposure and child IQ at age 5 years. Pediatrics doi: 10.1542/peds.2008-3506.
17. Lopez I, Beltran-Parrazal1 L, Abhimanyu Amarnani A. Evidence for oxidative stress in the developing cerebellum of the rat after chronic mild carbon monoxide exposure (0.0025% in air) BMC Neuroscience 2009, 10:53doi:10.1186/1471-2202-10-53
18. Zhou Z, Yuan T, Chen Y, Qu L, Rauh V, Zhang Y, Tang D, Perera F, Li T. Benefits of Reducing Prenatal Exposure to Coal-Burning Pollutants to Children's Neurodevelopment in China Research Article, published 14 Jul 2008 | doi:10.1289/ehp.11480
19. Thomson, E.M. et al. (2007) Air pollution alters brain and pituitary endothelin-1 and inducible nitric oxide synthase gene expression. Environ. Res. 105, 224233
20. Peters, A. et al. (2006) Translocation and potential neurological effects of fine and ultrafine particles a critical update. Part. Fibre Toxicol. 3, 13
21. Hong, Y.C. et al. (2002) Air pollution: a new risk factor in ischemic stroke mortality. Stroke 33, 2165-2169
22. Kettunen, J. et al. (2007) Associations of fine and ultrafine particulate air pollution with stroke mortality in an area of low air pollution levels. Stroke 38, 918-922
23. Calderon-Garciduenas, L. et al. (2002) Air pollution and brain damage. Toxicol. Pathol. 30, 373-389
24. Calderon-Garciduenas, L. et al. (2003) DNA damage in nasal and brain tissues of canines exposed to air pollutants is associated with evidence of chronic brain inflammation and neurodegeneration. Toxicol. Pathol. 31, 524-538
25. Mateen F, Brook R. Air Pollution as an Emerging Global Risk Factor for Stroke JAMA 2011;305(12):1240-1241.doi:10.1001/jama.2011.352
26. Lopez IA, Acuna D, Beltran-Parrazal L, Lopez IE, Amarnani A, Cortes M, Edmond J. Evidence for oxidative stress in the developing cerebellum of the rat after chronic mild carbon monoxide exposure (0.0025% in air) BMC Neuroscience 2009, 10:53 (27 May 2009)
27. Morgan TE, Davis DA, Iwata N, Tanner JA, Snyder D, Ning Z, et al. 2011. Glutamatergic Neurons in Rodent Models Respond to Nanoscale Particulate Urban Air Pollutants In Vivo and In Vitro. Environ Health Perspect :-. doi:10.1289/ehp.1002973
28. Gackiere F, Saliba L, Baude A, Bosler O, Strube C. Ozone inhalation activates stress-responsive regions of the central nervous system. J Neurochem. 2011 Apr 6. doi: 10.1111/j.1471-4159.2011.07267.x.
29. Calderon-Garciduenas L, D'Angiulli A, Kulesza RJ, Torres-Jardon R, Osnaya N, Romero L, Keefe S, Herritt L, Brooks DM, Avila-Ramirez J, Delgado-Chavez R, Medina-Cortina H, Gonzalez-Gonzalez LO. Air pollution is associated with brainstem auditory nuclei pathology and delayed brainstem auditory evoked potentials. Int J Dev Neurosci. 2011 Mar 31.
30. Power MC, Weisskopf MG, Alexeeff SE, Coull BA, Spiro A III, Schwartz J 2011. Traffic-Related Air Pollution and Cognitive Function in a Cohort of Older Men. Environ Health Perspect 119:682-687. doi:10.1289/ehp.1002767
31. Fonken LK, Xu X, Weil ZM, Chen G, Sun Q, Rajagopalan S, Nelson RJ. Air pollution impairs cognition, provokes depressive-like behaviors and alters hippocampal cytokine expression and morphology. Molecular Psychiatry, 2011; DOI: 10.1038/mp.2011.76
32. Levesque S, Surace MJ, McDonald J, Block ML. Air pollution and the brain: Subchronic diesel exhaust exposure causes neuroinflammation and elevates early markers of neurodegenerative disease. J Neuroinflammation. 2011 Aug 24;8(1):105.
33. Guxens M, Aguilera I, Ballester F, Estarlich M, Fernandez-Somoano A, Lertxundi A, Lertxundi N, Mendez MA, Tardon A, Vrijheid M, Sunyer J. Prenatal Exposure to Residential Air Pollution and Infant Mental Development: Modulation by Antioxidants and Detoxification Factors. Environ Health Perspect. 2011 Aug 25.
34. Calderon-Garciduenas L, Kavanaugh M, Block M, D'Angiulli A, Delgado-Chavez R, Torres-Jardon R, Gonzalez-Maciel A, Reynoso-Robles R, Osnaya N, Villarreal-Calderon R, Guo R, Hua Z, Zhu H, Perry G, Diaz P. Neuroinflammation, Alzheimer's Disease-Associated Pathology, and Down-Regulation of the Prion-Related Protein in Air Pollution Exposed Children and Young Adults. J Alzheimers Dis. 2011 Sep 28.
35. Calderon-Garciduenas L, Engle R, Mora-Tiscareno A, Styner M, Gomez-Garza G, Zhu H, Jewells V, Torres-Jardon R, Romero L, Monroy-Acosta ME, Bryant C, Gonzalez-Gonzalez LO, Medina-Cortina H, D'Angiulli A. Exposure to severe urban air pollution influences cognitive outcomes, brain volume and systemic inflammation in clinically healthy children. Brain Cogn. 2011 Oct 25.
36. Ranft U, Schikowski T, Sugiri D, Krutmann J, Kramer U. Long-term exposure to traffic-related particulate matter impairs cognitive function in the elderly. Environ Res. 2009 Nov;109(8):1004-11.
37. Henn BC, Schnaas L, Ettinger AS, Schwartz J, Lamadrid-Figueroa H, Hernandez-Avila M, et al. 2011. Associations of Early Childhood Manganese and Lead Coexposure with Neurodevelopment. Environ Health Perspect 120:126-131. http://dx.doi.org/10.1289/ehp.1003300
38. Ciesielski T, Weuve J, Bellinger DC, Schwartz J, Lanphear B, Wright RO 2012. Cadmium Exposure and Neurodevelopmental Outcomes in U.S. Children. Environ Health Perspect :-. http://dx.doi.org/10.1289/ehp.1104152
39. Weuve J, Puett R, Schwartz J, Yanosky J, Laden F, Grodstein F. Exposure to Particulate Air Pollution and Cognitive Decline in Older Women Arch Intern Med. 2012;172(3):219-227. doi:10.1001/archinternmed.2011.683
40. Perera FP, Tang D, Wang S, Vishnevetsky J, Zhang B, Diaz D, Camann D, Rauh V. Prenatal Polycyclic Aromatic Hydrocarbon (PAH) Exposure and Child Behavior at age 6-7. Environ Health Perspect. 2012 Mar 22.
41. Calderon-Garciduenas L, Serrano-Sierra A, Torres-Jardon R, Zhu H, Yuan Y, Smith D, Delgado-Chavez R, Cross JV, Medina-Cortina H, Kavanaugh M, Guilarte TR. The impact of environmental metals in young urbanites' brains. Exp Toxicol Pathol. 2012 Mar 19.
42. Lewis J, Bench G, Myers O, Tinner B, Staines W, Barr E, Divine KK, Barrington W, Karlsson J (2005) Trigeminal uptake and clearance of inhaled manganese chloride in rats and mice. Neurotoxicology 26:113-23.
43. Calderon-Garciduenas L, Mora-Tiscareno A, Styner M, Zhu H, Torres-Jardon R, Carlos E, Solorio-Lopez E, Medina-Cortina H, Kavanaugh M, D'Angiulli A. White Matter Hyperintensities, Systemic Inflammation, Brain Growth, and Cognitive Functions in Children Exposed to Air Pollution. J Alzheimers Dis. 2012 Apr 18.
44. Moulton PV, Yang W. Air pollution, oxidative stress, and Alzheimer's disease. J Environ Public Health. 2012;2012:472751.
45. Bos I, De Boever P, Emmerechts J, Buekers J, Vanoirbeek J, Meeusen R, Van Poppel M, Nemery B, Nawrot T, Panis LI. Changed gene expression in brains of mice exposed to traffic in a highway tunnel. Inhal Toxicol. 2012 Aug;24(10):676-86.
46. Boucher O, et al. Prenatal Methylmercury, Postnatal Lead Exposure, and Evidence of Attention Deficit/Hyperactivity Disorder among Inuit Children in Arctic Quebec. Environ Health Perspect 120:0000-0000 (2012). http://dx.doi.org/10.1289/ehp.1204976
47. Volk H, Lurmann F, Penfold B, Hertz-Picciotto I, McConnell R. Traffic-Related Air Pollution, Particulate Matter, and Autism. Arch Gen Psychiatry. 2012;():1-7. doi:10.1001/jamapsychiatry.2013.266.
48. Chen R, Zhang Y, Yang C, Zhao Z, Xu X, Kan H. Acute Effect of Ambient Air Pollution on Stroke Mortality in the China Air Pollution and Health Effects Study.Stroke. 2013 Feb 7.
49. Allen, JL, K Conrad, G Oberdorster, CJ Johnston, B Sleezer and BA Cory-Slechta. 2013. Developmental exposure to concentration ambient particles and preferences for immediate reward in mice. Environmental Health Perspectives 121(1): 32-38 http://dx.doi.org/10.1289/ehp.1205505.
50. Becerra T, Wilhelm M, Olsen J, Cockburn M, Ritz B. Ambient Air Pollution and Autism in Los Angeles County, California. Environ Health Perspect 121:380-386 (2013).?http://dx.doi.org/10.1289/ehp.1205827
51. Lucchini, RG, S Zoni, S Guazzetti, E Bontempi, S Micheletti, K Broberg, G Parrinello and DR Smith. 2012. Inverse association of intellectual function with very low blood lead but not with manganese exposure in Italian adolescents. Environmental Research http://dx.doi.org/10.1016/j.envres.2012.08.003.